The Arizona Diamondbacks (50-106) open their final Road Series of the year against the NFL West-leading San Francisco Giants (102-54). The first pitch is at 9:45 p.m. ET in Oracle Park. Let’s analyze the lines around Diamondbacks vs. Giants odds with MLB picks and predictions.

Diamondbacks RHP Luke Weaver (3-6, 4.38 ERA) is making his 13th start. He has 1.15 WHIP, 2.3 BB / 9 and 8.2 K / 9 to 61 2/3 IP.

Giants RHP Logan Webb (10-3, 3.04 ERA) is making his 25th start. He has 1.12 WHIP, 2.2 BB / 9 and 9.5 K / 9 to 136 1/3 IP.

MLB odds courtesy of Tipico Sportsbook; Visit USA TODAY Sports for a full list. The odds were last updated at 14:00. ET.

The Giants are 14-2 against the Diamondbacks this season. You have won 16 of the last 20 games. They are at home 49:26 this season and 19-5 overall when Webb starts.

The Diamondbacks have only taken five wins in their last 21 games. Her 30-48 street record is the worst in the National League and the second worst in the majors.

This bet doesn’t have much value, but it’s a sure win. Take the GIANTS (-280).

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With 36-42 ATS on the road, the Diamondbacks have the fifth worst grade in the majors. These last seven defeats were all caused by at least two runs. Nine of their 14 losses to the Giants were caused by two or more runs.

The Giants are third in the majors with a 41-34 home ATS record. 13 of their 16 wins in the last 20 games were achieved by at least two runs.

Thirteen of the 16 games between the two teams this season had a total of 8 or more runs.

The Giants’ last six games and 14 of the last 20 have all had at least eight runs.

Gannett earns income from referring spectators to betting services. Newsrooms are independent of this relationship and have no influence on the reporting. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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Wetten 101 – Education and Tips for Sports Betting Beginners September 28, 2021 3:12 PM ET

By: SportsbookWire Staff

Would you like to get started with sports betting? We explain what you need to know to bet on the money line, point spread and total.

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